Updated Mayo Algorithm
- 5 days ago
- 1 min read
The best and most authoritative guide to Treating RLS has just got better. Updated this May 2026, the new Mayo Algorithm refines and clarifies the best practice treatment of RLS including:
Increased emphasis on iron therapy even at higher ferritin levels
Clear focus on 3 main strategies of Iron Therapy, Gabapentinoids and Low Dose Opioids
Guidelines for managing augmentation and safe withdrawal from dopmanine agonists